Parenteral Nutrition, Sepsis, Acute Heart Failure and Hepatotoxic Drugs Are Related to Liver Test Disturbances in Critically Ill Patients

Analysis of the relative impact of parenteral nutrition on liver dysfunction in critically ill patients, characterizing the presence of pre-existing liver disturbances, acute heart failure, sepsis, daily parenteral nutrition volume, and commonly used hepatotoxic drugs in adult ICU patients, together with daily aspartate aminotransferase, alanine aminotransferase, gamma-glutamyltransferase, alkalic phosphatase, total bilirubin, and INR values.

Hypercholesterolemia and hypertriglyceridemia as risk factors of liver dysfunction in children with inflammation receiving total parenteral nutrition.

AIM: to evaluate the association between use of total parenteral nutrition exclusively and changes in hepatic profile, and investigation between age, hypertriglyceridemia, and hypercholesterolemia, and the occurrence of liver dysfunction.